Wireline logs were used to characterize sequence stratigraphic relationships and depositional environments of the Silurian strata in the southeastern Ghadames Basin between Libya and Tunisia in order to delineate prospective reservoirs that will benefit future exploration programs. Gamma ray log signatures revealed a variety of different sedimentological environments, each of which were represented by different depositional facies such as lowstand systems tract (LST) fluvial channels, highstand systems tract (HST) progradational sand, and transgressive systems tract (TSTs) condensed sections, all of which have their own unique characteristics. The link correlation between Libya and Tunisia was established using eight boreholes in order to create a regional correlation that displayed a wide range of sedimentological packages. The study included fifteen sequences, each reflecting a different time period, eustatic levels, and environmental conditions that could be seen shifting laterally throughout the course of the timeline. The study revealed that Libya has a higher total sand ratio, which includes the majority of regressive cycles, as compared to Tunisia.